BDBM558748 4-((3-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-oxoimidazolidin-::US11365205, Example 18

SMILES OC(CN1CCN(Cc2ccc(cc2)C#N)C1=O)CN1CCc2ccccc2C1

InChI Key InChIKey=BDOGXDDYLRSPFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558748   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558748(4-((3-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydro...)
Affinity DataIC50:  70nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent