BDBM558789 (R)-1-((5-(3,3-difluoropyrrolidine-1-carbonylpyridin-2-yl)methyl)-3-(3-(3,4-::US11365205, Example 56

SMILES O[C@@H](CN1CCN(Cc2ccc(cn2)C(=O)N2CCC(F)(F)C2)C1=O)CN1CCc2ccccc2C1

InChI Key InChIKey=WPWTYQBLLPEVPT-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558789   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558789((R)-1-((5-(3,3-difluoropyrrolidine-1-carbonylpyrid...)
Affinity DataIC50:  30nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent