BDBM558805 (R)-1-((2-((1-acetylpiperidin-4-yl)amino)pyridin-4-yl)methyl)-3-(3-(3,4-::US11365205, Example 72

SMILES CC(=O)N1CCC(CC1)Nc1cc(CN2CCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)ccn1

InChI Key InChIKey=ISROTIMDIBEBDY-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558805   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558805((R)-1-((2-((1-acetylpiperidin-4-yl)amino)pyridin-4...)
Affinity DataIC50:  40nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent