BDBM5593 2-arylamino-pyrimidine deriv. 9c::6-(cyclohexylmethoxy)-2-N-[4-(methylsulfanyl)phenyl]-5-nitrosopyrimidine-2,4-diamine

SMILES CSc1ccc(Nc2nc(N)c(N=O)c(OCC3CCCCC3)n2)cc1

InChI Key InChIKey=JBKFSYGZKCTBDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5593   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Newcastle

LigandPNGBDBM5593(2-arylamino-pyrimidine deriv. 9c | 6-(cyclohexylme...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5593(2-arylamino-pyrimidine deriv. 9c | 6-(cyclohexylme...)
Affinity DataIC50:  220nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed