BDBM559784 WO2022109182, Example 15

SMILES CC(C)(Cn1c(CN2CCC(CC2)c2cccc(OCc3ccc(cc3F)C#N)n2)nc2c(F)cc(cc12)C(O)=O)C#N

InChI Key InChIKey=XYFKVQYXGQZEGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559784   

TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559784(WO2022109182, Example 15)
Affinity DataIC50:  0.240nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed