BDBM560635 (2R,4R)-4-((3-fluoro-6- ((5-methyl-1H-pyrazol-3- yl)amino)pyridin-2-yl) methyl)-2-methyl-1-(3- (trifluoromethyl)benzyl) piperidine-4-carboxylic acid::US11384066, Example 21

SMILES C[C@@H]1C[C@@](Cc2nc(Nc3cc(C)[nH]n3)ccc2F)(CCN1Cc1cccc(c1)C(F)(F)F)C(O)=O

InChI Key InChIKey=JNUOYJIFPAGVNI-VOIUYBSRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560635   

TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560635((2R,4R)-4-((3-fluoro-6- ((5-methyl-1H-pyrazol-3- y...)
Affinity DataIC50:  5.55E+3nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560635((2R,4R)-4-((3-fluoro-6- ((5-methyl-1H-pyrazol-3- y...)
Affinity DataIC50:  3.10nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent