BDBM560640 (2R,4R)-1-(3-chloro-2- fluorobenzyl)-4-((4-fluoro- 6-((5-methyl-1H-pyrazol- 3-yl)amino)pyridin-2- yl)methyl)-2- methylpiperidine-4- carboxylic acid::US11384066, Example 30

SMILES C[C@@H]1C[C@@](Cc2cc(F)cc(Nc3cc(C)[nH]n3)n2)(CCN1Cc1cccc(Cl)c1F)C(O)=O

InChI Key InChIKey=SEYBQYNGNHTWDW-OYLFLEFRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560640   

TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560640((2R,4R)-1-(3-chloro-2- fluorobenzyl)-4-((4-fluoro-...)
Affinity DataIC50:  860nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560640((2R,4R)-1-(3-chloro-2- fluorobenzyl)-4-((4-fluoro-...)
Affinity DataIC50:  1.10nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent