BDBM560651 (2R,4R)-1-(2,3-dichloro- benzyl)-4-((3-fluoro-4- methyl-6- ((5-methyl-1H-pyrazol-3-yl)- amino)pyridin-2-yl)methyl)-2- methylpiperidine-4-carboxylic acid::US11384066, Example 53

SMILES C[C@@H]1C[C@@](Cc2nc(Nc3cc(C)[nH]n3)cc(C)c2F)(CCN1Cc1cccc(Cl)c1Cl)C(O)=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560651   

TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560651((2R,4R)-1-(2,3-dichloro- benzyl)-4-((3-fluoro-4- m...)
Affinity DataIC50:  309nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560651((2R,4R)-1-(2,3-dichloro- benzyl)-4-((3-fluoro-4- m...)
Affinity DataIC50:  0.550nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent