BDBM560654 1-(3-chloro-2-fluorobenzyl)- 4-((4-ethyl-3-fluoro-6-((5-methyl- 1H-pyrazol-3-yl)amino)- pyridin-2-yl)methyl)piperidine- 4-carboxylic acid::US11384066, Example 66

SMILES CCc1cc(Nc2cc(C)[nH]n2)nc(CC2(CCN(Cc3cccc(Cl)c3F)CC2)C(O)=O)c1F

InChI Key InChIKey=QOYWSCMDSDPETI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 560654   

TargetAurora kinase B(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560654(1-(3-chloro-2-fluorobenzyl)- 4-((4-ethyl-3-fluoro-...)
Affinity DataIC50:  408nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM560654(1-(3-chloro-2-fluorobenzyl)- 4-((4-ethyl-3-fluoro-...)
Affinity DataIC50:  0.570nMAssay Description:Experimental Methods:(1) Prepare a 1× kinase buffer [50 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), PH 7.5, 0.01% Brij-35, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent