BDBM562398 (rac)-15-chloro-14-ethyl-1-(3-((6-fluoronaphthalen-1-yl)oxy)propyl)-8,13-dimethyl-11-(rac)-morpholino-5,6,9,10,11,13-hexahydro-4H,8H-pyrazolo[3',4':6,7][1]thia[2,10]diazacyclotridecino[8,9,10-hi]indole-2-carboxylic acid 7,7-dioxide (Mixture of Stereoisomers)::US11401278, Example 69

SMILES CCc1c-2c(nn1C)C(CCN(C)S(=O)(=O)CCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13)N1CCOCC1

InChI Key InChIKey=SOSFJVGXMDRHJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562398   

LigandPNGBDBM562398((rac)-15-chloro-14-ethyl-1-(3-((6-fluoronaphthalen...)
Affinity DataIC50:  1.5nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent