BDBM563665 1-[2-Fluoro-4-(pyridin-4-yloxy)- phenyl]-3-[5-(2-hydroxy-1,1- dimethyl-ethyl)-2-p-tolyl-2H- pyrazol-3-yl]-urea::US11407771, Compound 279

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccncc2)cc1F)C(C)(C)CO

InChI Key InChIKey=AXWYEUZFKJYMQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563665   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563665(1-[2-Fluoro-4-(pyridin-4-yloxy)- phenyl]-3-[5-(2-h...)
Affinity DataIC50:  64nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM563665(1-[2-Fluoro-4-(pyridin-4-yloxy)- phenyl]-3-[5-(2-h...)
Affinity DataIC50:  625nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent