BDBM563771 Roche-Dataset for PDE10A, Compound 85
SMILES COc1cccc(c1)-c1nc2cc(NC(=O)c3c(cnn3C)C(=O)N3CCC3)ccn2n1
InChI Key InChIKey=IZHHUVHZKJCWMX-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 563771
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 0.310nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair