BDBM567965 US11420970, Example 166

SMILES COc1ccc(-c2cc(Cn3cnc4c(N)ncnc34)c(cn2)N2CCC[C@@](N)(C2)[C@@H](O)C(F)F)c(c1)C(F)(F)F

InChI Key InChIKey=OIEVISJMZRPXHV-SQJMNOBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 567965   

TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM567965(US11420970, Example 166)
Affinity DataIC50:  5.5nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent