BDBM568017 US11420970, Example 219

SMILES Nc1ncnc2n(Cc3cc(ncc3N3CCC[C@@](N)(C3)c3cc(O)cc(Cl)n3)-c3ccc(F)c(F)c3)cnc12

InChI Key InChIKey=ZNWRIPLSMSPHMF-HHHXNRCGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 568017   

TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM568017(US11420970, Example 219)
Affinity DataIC50:  5.5nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent