BDBM570186 US11427593, Compound ZB-BD-217
SMILES CCS(=O)(=O)Cc1cnc(OC2CCC(F)(F)CC2)c(c1)-c1cc(C)c2n1cc[nH]c2=O
InChI Key InChIKey=RAWLEIFPPTUFAB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 570186
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 20.9nMAssay Description:AlphaScreen kit (Perkin Elmer) was used to detect effect of the compounds on binding of BRD4 bromodomain to acetylated histone H4 polypeptide. The br...More data for this Ligand-Target Pair