BDBM570506 N-(2,4-dichloro-6-meth- ylbenzyl)-5-fluoro-8-hy- droxy-8-(methoxymeth- yl)-5,6,7,8-tetrahydro- quinoline-5- carboxamide::US11439633, Example 39

SMILES COCC1(O)CCC(F)(C(=O)NCc2c(C)cc(Cl)cc2Cl)c2cccnc12

InChI Key InChIKey=MNLDMEWYCHCMAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570506   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM570506(N-(2,4-dichloro-6-meth- ylbenzyl)-5-fluoro-8-hy- d...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent