BDBM570518 (5S*,8R*)-N- (2,4-dichlorobenzyl)-5- fluoro-8-hydroxy- 8-((3-hydroxyazeti- din-1-yl)methyl)-5,6,7,8- tetrahydroquinoline-5- carboxamide::US11439633, Example 51

SMILES OC1CC(C1)N[C@]1(O)CC[C@@](F)(C(=O)NCc2ccc(Cl)cc2Cl)c2cccnc12

InChI Key InChIKey=ZMFFQCUWNJSUQV-FYPKQTSISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570518   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM570518((5S*,8R*)-N- (2,4-dichlorobenzyl)-5- fluoro-8-hydr...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent