BDBM570522 (5S*,8R*)-N-(2-chloro- 4-fluorobenzyl)-5- fluoro-8-hydroxy-8-((3- methoxy-3-methyl- azetidin-1-yl)methyl)- 5,6,7,8-tetrahydro- quinoline-5- carboxamide::US11439633, Example 55

SMILES COC1(C)CC(C1)N[C@]1(O)CC[C@@](F)(C(=O)NCc2ccc(F)cc2Cl)c2cccnc12

InChI Key InChIKey=UXJBTOGHEKRIIY-PCBKEIHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570522   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Raqualia Pharma

US Patent
LigandPNGBDBM570522((5S*,8R*)-N-(2-chloro- 4-fluorobenzyl)-5- fluoro-8...)
Affinity DataIC50: <50nMAssay Description:The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensitive fluorescent dy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent