BDBM571415 US11440922, Example 40::methyl (4E)-4-[3-(3- chlorophenyl)prop-2-yn-1- ylidene]-3,3- dimethylpiperidine-1- carboxylate
SMILES COC(=O)N1CC\C(=C/C#Cc2cccc(Cl)c2)C(C)(C)C1
InChI Key InChIKey=OJFFNJQXZCGSMM-OVCLIPMQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 571415
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Industria Chimica E Farmacentica
US Patent
Recordati Industria Chimica E Farmacentica
US Patent
Affinity DataKi: 1.29nMAssay Description:Affinity at transmembrane glutamate metabotropic cloned human mGluR5 receptor was evaluated according to the methods of Anderson (Anderson et al., J ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Industria Chimica E Farmacentica
US Patent
Recordati Industria Chimica E Farmacentica
US Patent
Affinity DataIC50: 18.2nMAssay Description:Cells were seeded into black-walled, clear-bottom, 96-well plates at a density of 80000 cell/well, in RPMI (without Phenol Red, without L-glutamine; ...More data for this Ligand-Target Pair