BDBM572598 2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-(trifluoromethoxy)phenyl)thiazol-2-yl)propanamide::US11453663, Preparative Example 136

SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc(OC(F)(F)F)cc2)cc1O

InChI Key InChIKey=RTFHXRDUBVOTKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 572598   

TargetDouble-strand break repair protein MRE11(Homo sapiens (Human))
Masarykova Univerzita

US Patent
LigandPNGBDBM572598(2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-(4-(trifluoro...)
Affinity DataIC50:  6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent