BDBM572746 2-cyano-N-(5-cyclohexyl-4-phenylthiazol-2-yl)-3-(3,4-dihydroxyphenyl)propanamide::US11453663, Preparative Example 146

SMILES Oc1ccc(CC(C#N)C(=O)Nc2nc(c(s2)C2CCCCC2)-c2ccccc2)cc1O

InChI Key InChIKey=MLHGEWHWEBMZDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 572746   

TargetDouble-strand break repair protein MRE11(Homo sapiens (Human))
Masarykova Univerzita

US Patent
LigandPNGBDBM572746(2-cyano-N-(5-cyclohexyl-4-phenylthiazol-2-yl)-3-(3...)
Affinity DataIC50:  6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent