BDBM572804 3-(3-chloro-4-hydroxy-5-methylphenyl)-2-cyano-N-(4-phenylthiazol-2-yl)propanamide::US11453663, Preparative Example 155

SMILES Cc1cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccccc2)cc(Cl)c1O

InChI Key InChIKey=UUGDXHOTOITNFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 572804   

TargetDouble-strand break repair protein MRE11(Homo sapiens (Human))
Masarykova Univerzita

US Patent
LigandPNGBDBM572804(3-(3-chloro-4-hydroxy-5-methylphenyl)-2-cyano-N-(4...)
Affinity DataIC50:  5.00E+4nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent