BDBM574589 US11458149, Compound I-190 isomer 1

SMILES C[C@@]1(CC(Br)=NO1)C1CCN(Cc2ccc(cc2)C(F)(F)F)CC1

InChI Key InChIKey=RSFSLGYFRKACTN-MRXNPFEDSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574589   

TargetTranscriptional enhancer factor TEF-1(Homo sapiens)
Ikena Oncology

US Patent
LigandPNGBDBM574589(US11458149, Compound I-190 isomer 1)
Affinity DataEC50: <100nMAssay Description:TEAD inhibition can be assayed using Hippo Pathway TEAD Reporter—MCF7 Cell Line (BPS Bioscience, Catalog #: 60618).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent