BDBM575662 US11464802, Compound 25
SMILES CC1CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(CC2)[C@H](F)c2nncn2C)CCC1(F)F
InChI Key InChIKey=PBKRYWFMNRFAII-FZYLFJGDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 575662
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics
US Patent
Nurix Therapeutics
US Patent
Affinity DataIC50: 3nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair