BDBM576049 4-(1-benzyl-2-methyl-1H- imidazo[4,5-b]pyridin-6-yl)-6- methyl-1H-pyrrolo[2,3-c] pyridin-7(6H)-one::US11466034, Example 6

SMILES Cc1nc2ncc(cc2n1Cc1ccccc1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=NTRXALHVKBFJRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576049   

TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576049(4-(1-benzyl-2-methyl-1H- imidazo[4,5-b]pyridin-6-y...)
Affinity DataIC50:  2.80nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [44-167](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576049(4-(1-benzyl-2-methyl-1H- imidazo[4,5-b]pyridin-6-y...)
Affinity DataIC50:  7.60nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent