BDBM576083 Compound 36 (4-(1-(2,6-dichlorobenzyl)-1H-pyrrolo[3,2-b]pyridin-6-yl)-6-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)::US11466034, Example 36

SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc2c(cn(C)c(=O)c12)-c1cnc2ccn(Cc3c(Cl)cccc3Cl)c2c1

InChI Key InChIKey=ZKKHYHXPEWCLEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576083   

TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576083(Compound 36 (4-(1-(2,6-dichlorobenzyl)-1H-pyrrolo[...)
Affinity DataIC50:  2.90nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [44-167](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576083(Compound 36 (4-(1-(2,6-dichlorobenzyl)-1H-pyrrolo[...)
Affinity DataIC50:  15nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent