BDBM576088 N-(1-(4-chlorobenzyl)-2- methyl-6-(6-methyl-7-oxo-6,7- dihydro-1H-pyrrolo[2,3-c] pyridin-4-yl)-1H-benzo[d] imidazol-4-yl)ethane- sulfonamide::US11466034, Example 41

SMILES CCS(=O)(=O)Nc1cc(cc2n(Cc3ccc(Cl)cc3)c(C)nc12)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=CDTQQFOUFQKDDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576088   

TargetBromodomain-containing protein 4 [349-460](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576088(N-(1-(4-chlorobenzyl)-2- methyl-6-(6-methyl-7-oxo-...)
Affinity DataIC50:  0.400nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [44-167](Homo sapiens (Human))
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576088(N-(1-(4-chlorobenzyl)-2- methyl-6-(6-methyl-7-oxo-...)
Affinity DataIC50:  1nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent