BDBM576221 WO2022109573, Compound 7

SMILES Nc1cc(c2nc1-c1nnc(o1)[C@@](O)(CCCCC[C@H]1CCCN21)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=KOJWRORRAOCIFZ-BTDLBPIBSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576221   

TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals

WIPO
LigandPNGBDBM576221(WO2022109573, Compound 7)
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed