BDBM576625 US11472776, Example 14

SMILES COc1ccc(cn1)-n1c(nc2ccsc2c1=O)-c1cccnc1

InChI Key InChIKey=LYVCSNUACUVVTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576625   

TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Oligomerix

US Patent
LigandPNGBDBM576625(US11472776, Example 14)
Affinity DataIC50:  2.23E+4nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Oligomerix

US Patent
LigandPNGBDBM576625(US11472776, Example 14)
Affinity DataIC50:  6.25E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent