BDBM577094 (7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,8-dihydropyrido[2′,3′: 4,5]pyrrolo[1,2-a]pyrazin-9(6H)-one ::US11472805, Example 11

SMILES C[C@H]1Cn2c(c(-c3ccc(Cl)cc3)c3ncccc23)C(=O)N1C1CC1

InChI Key InChIKey=WAYXCSKMOOKIDO-LBPRGKRZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577094   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM577094((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50: <0.300nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577094((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50:  28.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577094((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50: <0.570nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM577094((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50: <0.520nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent