BDBM577121 9-(4-Chlorophenyl)-7-cyclopropyl-6,7-dihydro[1,3]thiazolo[4',5':4,5]pyrrolo[1,2-a]pyrazin-8(5H)-one::US11472805, Example 27
SMILES Clc1ccc(cc1)-c1c2C(=O)N(CCn2c2scnc12)C1CC1
InChI Key InChIKey=IMNGGIXQGKWJJB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 577121
Affinity DataIC50: 2.28nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
TargetIsoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672](Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736](Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent