BDBM580006 US11485736, Compound Table 2.15::US11485736, Compound Table 3.23

SMILES COc1ncnc(C2CC2)c1-c1ncc2cnn(Cc3ccc(cc3)-c3nc(cn3C)C(F)(F)F)c2n1

InChI Key InChIKey=PVMLMBZHJPOSHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 580006   

TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Ksq Therapeutics

US Patent
LigandPNGBDBM580006(US11485736, Compound Table 2.15 | US11485736, Comp...)
Affinity DataIC50:  55nMAssay Description:Deubiquitinase activity was measured using ubiquitin-rhodamine 110 as a substrate. Cleavage of the amide bond between rhodamine and the c-terminal gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 1(Homo sapiens (Human))
Ksq Therapeutics

US Patent
LigandPNGBDBM580006(US11485736, Compound Table 2.15 | US11485736, Comp...)
Affinity DataIC50:  55nMAssay Description:Deubiquitinase activity was measured using ubiquitin-rhodamine 110 as a substrate. Cleavage of the amide bond between rhodamine and the c-terminal gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent