BDBM580475 3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-5-yl)methyl]-5-(2-propoxy-3- pyridyl)pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11491140, Example 68

SMILES CCCOc1ncccc1-c1cc(NCc2nnn(C)n2)c2n(nc(C)c2n1)[C@@H](C)CC

InChI Key InChIKey=DGDYHVXCROBNNK-AWEZNQCLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580475   

LigandPNGBDBM580475(3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...)
Affinity DataIC50:  0.790nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM580475(3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...)
Affinity DataIC50:  1.30nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM580475(3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...)
Affinity DataIC50:  0.140nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent