BDBM580557 5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1- methylimidazol-4-yl)methyl]-1-[1- methylpropyl]pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11491140, Example 132

SMILES CCOc1ncccc1-c1cc(NCc2cn(C)cn2)c2n(nc(C)c2n1)[C@@H](C)CC

InChI Key InChIKey=NIXYLBKMUOTNON-HNNXBMFYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580557   

LigandPNGBDBM580557(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1- methylimida...)
Affinity DataIC50:  0.140nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM580557(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1- methylimida...)
Affinity DataIC50:  0.520nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM580557(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(1- methylimida...)
Affinity DataIC50:  0.0450nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent