BDBM580691 US11492346, Example 31

SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)c(cc12)C1CC1

InChI Key InChIKey=MJHNXUDLBLHFTD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580691   

TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580691(US11492346, Example 31)
Affinity DataKi:  0.320nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580691(US11492346, Example 31)
Affinity DataKi:  0.890nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580691(US11492346, Example 31)
Affinity DataKi:  56nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent