BDBM580735 US11492346, Example 75

SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3cc(C)cc(F)c3)c12

InChI Key InChIKey=NJOCRNULHUQEOU-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 580735   

TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580735(US11492346, Example 75)
Affinity DataKi:  6.42nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580735(US11492346, Example 75)
Affinity DataKi:  9.13nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580735(US11492346, Example 75)
Affinity DataKi:  13.8nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580735(US11492346, Example 75)
Affinity DataKi:  320nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580735(US11492346, Example 75)
Affinity DataKi:  5.70E+3nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580735(US11492346, Example 75)
Affinity DataKi:  1.25E+4nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent