BDBM580883 3-((3-(2-aminopyrimidin-5-yl)-5- morpholinophenyl)sulfonyl)-N,N- dimethylazetidine-1-carboxamide::US11492348, Compound 95
SMILES CN(C)C(=O)N1CC(C1)S(=O)(=O)c1cc(cc(c1)-c1cnc(N)nc1)N1CCOCC1
InChI Key InChIKey=HHRCZUVDMACSEU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 580883
TargetRAC-alpha serine/threonine-protein kinase [1-472,474-480](Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of the PI3K-AKT-mTOR pathway was measured by quantifying the loss of (Ser-473) pAKT using AlphaScreen (Perkin Elmer). B103 (Rat Neuroblast...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 120nMAssay Description:Quantification of ATP to ADP conversion as a measure of PI3Kα activity. Active PI3Kα (Life Technologies), in the presence or absence of PI3...More data for this Ligand-Target Pair