BDBM581102 US11504364, Compound 98

SMILES CC(=O)Nc1cccc(c1)-c1ccc2nccc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)c2c1

InChI Key InChIKey=JKSSGZRGDCLHNG-IBGZPJMESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 581102   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Praxis Biotech

US Patent
LigandPNGBDBM581102(US11504364, Compound 98)
Affinity DataIC50: >1.00E+4nMAssay Description:FAPα enzymatic exopeptidase (dipeptidase) activity assay. To assay baseline FAPa enzymatic exopeptidase activity, 40 ng of recombinant human FAP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPresequence protease, mitochondrial(Homo sapiens (Human))
Praxis Biotech

US Patent
LigandPNGBDBM581102(US11504364, Compound 98)
Affinity DataIC50: <1.00E+3nMAssay Description:PREP enzymatic activity assay. To assay baseline prolyl endopeptidase (PREP) activity, 20 ng of recombinant human PREP (rhPREP) (R&S system, #4308-SE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Praxis Biotech

US Patent
LigandPNGBDBM581102(US11504364, Compound 98)
Affinity DataIC50: <1.00E+3nMAssay Description:DPPIV enzymatic activity assay. To assay baseline dipeptidyl peptidase-4 (DPPIV) activity, 40 ng of recombinant human DPPIV (rhDPPIV) (R&S system, #1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Praxis Biotech

US Patent
LigandPNGBDBM581102(US11504364, Compound 98)
Affinity DataIC50: >1.00E+4nMAssay Description:DPP9 enzymatic activity assay. To assay baseline dipeptidyl peptidase 9 (DPP9) activity, 40 ng of recombinant human DPP9 (rhDPP9) (R&S system, #5419-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent