BDBM581594 (2s,4s)-2-[2-[3-(Trifluoromethoxy)phenyl]-7-azaspiro[3.5]nonane-7-carbonyl)-7- oxa-5-azaspiro[3.4]octan-6-one::US11505546, Example 9

SMILES FC(F)(F)Oc1cccc(c1)C1CC2(C1)CCN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2

InChI Key InChIKey=IJGCJPVHSVKODV-NBEIKUQISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581594   

TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581594((2s,4s)-2-[2-[3-(Trifluoromethoxy)phenyl]-7-azaspi...)
Affinity DataIC50:  0.0940nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent