BDBM581638 (rac)-(2s,4s)-2-(6-Cyclohexyl-2-azaspiro[3.4]octane-2-carbonyl)-7-oxa-5- azaspiro[3.4]octan-6-one::US11505546, Example 53::US11505546, Example 54

SMILES O=C([C@H]1C[C@@]2(C1)COC(=O)N2)N1CC2(C1)CCC(C2)C1CCCCC1

InChI Key InChIKey=PWPWXTRHSIWNGI-KXOVQGTASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581638   

TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581638((rac)-(2s,4s)-2-(6-Cyclohexyl-2-azaspiro[3.4]octan...)
Affinity DataIC50:  3.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM581638((rac)-(2s,4s)-2-(6-Cyclohexyl-2-azaspiro[3.4]octan...)
Affinity DataIC50:  0.710nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent