BDBM589202 US11548903, Example 130
SMILES [H][C@@]12CN(C[C@@]1(N=C(N)SC2)c1cc(\C=C(/F)c2ccc(cn2)C#N)ccc1F)c1nc(C)c(F)c(OC)n1
InChI Key InChIKey=ZOLASYMXTWTSAU-AIELCWNPSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 589202
Affinity DataIC50: 0.405nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.58E+4nMAssay Description:Recombinant CatD was expressed in CHO cells. The assay buffer for CatD was 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The CatD enzyme (9 nM) ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.78nMAssay Description:The cDNAs for both human recombinant BACE1 and 2 with C-terminal 6-His Tags were cloned into transient protein expression vectors, which were subsequ...More data for this Ligand-Target Pair