BDBM589752 US11559537, Compound 5291-(8J)

SMILES CC[C@@H](C)C(N)C(=O)N1Cc2ccc(F)cc2C1

InChI Key InChIKey=MMZVCOZOFNZWBM-CGCSKFHYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 589752   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50:  5.10nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50:  4.70nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50:  7.90E+3nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 8/9(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50:  58nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50: >1.00E+5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50: >1.00E+5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM589752(US11559537, Compound 5291-(8J))
Affinity DataIC50:  3.00E+4nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent