BDBM589996 (R)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl)-1-(3-(4,4-difluoropiperidin-1-yl)bicyclo[1.1.1]pentan-1-yl)-1H-imidazol-2-yl)-2-methylpropan-1-ol::US11560366, Example 8a

SMILES CC(C)[C@@H](O)c1nc(cn1C12CC(C1)(C2)N1CCC(F)(F)CC1)-c1cnc(N)c(OC(F)(F)F)c1

InChI Key InChIKey=JKCSVDDIGSSBDK-MDMXATFFSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 589996   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM589996((R)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...)
Affinity DataKd:  0.5nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent