BDBM59062 4-(3-methylbutyl)-1-sulfanylidene-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one::4-isoamyl-1-thioxo-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one::MLS001172777::SMR000595764::US20230365568, Compound 25::cid_2120341

SMILES CC(C)CCn1c2n[nH]c(=S)n2c2ccccc2c1=O

InChI Key InChIKey=CDNKKHCCJLPULM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59062   

TargetLarge T antigen(Simian virus 40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM59062(4-(3-methylbutyl)-1-sulfanylidene-2H-[1,2,4]triazo...)
Affinity DataEC50: >5.00E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
The United States of America,As Represented By The Secretary,Department of Health and Human Services

US Patent
LigandPNGBDBM59062(4-(3-methylbutyl)-1-sulfanylidene-2H-[1,2,4]triazo...)
Affinity DataIC50:  1.73E+3nMAssay Description:An ELISA-based PBD-binding inhibition assay was performed essentially as described previously. Briefly, a biotinylated PBIP1 p-T78 peptide (i.e., Bio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA dC->dU-editing enzyme APOBEC-3G(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM59062(4-(3-methylbutyl)-1-sulfanylidene-2H-[1,2,4]triazo...)
Affinity DataIC50:  1.19E+3nMT: 2°CAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay