BDBM59097 Aminopyrimidine, 10

SMILES CNc1nc(C)c(s1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1

InChI Key InChIKey=GAKKPKBEHVIOLH-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59097   

TargetG1/S-specific cyclin-D1(Homo sapiens (Human))
Cyclacel

LigandBDBM59097(Aminopyrimidine, 10)Copy SMILESCopy InChI

Affinity DataIC50:  7nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL

LigandBDBM59097(Aminopyrimidine, 10)Copy SMILESCopy InChI

Affinity DataIC50:  219nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetG1/S-specific cyclin-E1(Homo sapiens (Human))
Cyclacel

LigandBDBM59097(Aminopyrimidine, 10)Copy SMILESCopy InChI

Affinity DataIC50:  220nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI