BDBM594201 US11584746, Compound I-18
SMILES Fc1ccc2Nc3ccc(cc3C(=O)N(Cc3cccc4cc[nH]c34)c2c1)-c1ccc(cc1)N1CCNCC1
InChI Key InChIKey=VRHGKBQUNFUATG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 594201
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: <250nMAssay Description:IC50 values were determined at both 1 μM and 1 mM ATP to identify both ATP competitive and non-competitive compounds. Hits were also counter-scr...More data for this Ligand-Target Pair