BDBM594201 US11584746, Compound I-18

SMILES Fc1ccc2Nc3ccc(cc3C(=O)N(Cc3cccc4cc[nH]c34)c2c1)-c1ccc(cc1)N1CCNCC1

InChI Key InChIKey=VRHGKBQUNFUATG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594201   

TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM594201(US11584746, Compound I-18)
Affinity DataIC50: <250nMAssay Description:IC50 values were determined at both 1 μM and 1 mM ATP to identify both ATP competitive and non-competitive compounds. Hits were also counter-scr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent