BDBM594208 US11584746, Compound I-25
SMILES CN1CCC(CC1)n1cc(cn1)-c1ccc2Nc3ccc(F)cc3N(Cc3cccc4cc[nH]c34)C(=O)c2c1
InChI Key InChIKey=RJVBSURNERKLIH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 594208
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: <250nMAssay Description:IC50 values were determined at both 1 μM and 1 mM ATP to identify both ATP competitive and non-competitive compounds. Hits were also counter-scr...More data for this Ligand-Target Pair