BDBM595495 US11591319, ID lqr-8-180

SMILES CS(=O)(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccco1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=CQCSYBMTVJTOHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595495   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM595495(US11591319, ID lqr-8-180)
Affinity DataIC50:  2.72E+3nMAssay Description:Inhibition of biotin-linker-Beclin 1 BH3 peptide binding to human C-terminal 6His-tagged Bcl-2 (1 to 218 residues) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBeclin 1/Bcl-2(Homo sapiens)
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM595495(US11591319, ID lqr-8-180)
Affinity DataIC50:  2.77E+3nMAssay Description:A high-throughput Beclin 1/Bcl-2 AlphaLISA assay to directly measure the in vitro interaction between Beclin 1 and Bcl-2. AlphaLISA is a bead-based p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent