BDBM595809 US11591336, Compound 128::US11591336, Compound 129::US11591336, Compound 186
SMILES CN1CCN(c2n[nH]c3nc(cnc23)N2CCC(C)(CN)CC2)c2cccnc12
InChI Key InChIKey=VFDUCHULCOJIPO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 595809
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair