BDBM595821 US11591336, Compound 131
SMILES Cn1cc(cn1)-c1c2CCCN(c3n[nH]c4nc(cnc34)N3CCC(C)(CN)CC3)c2ccc1C#N
InChI Key InChIKey=HMIHWPOYAYDTHL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 595821
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
D. E. Shaw Research
US Patent
D. E. Shaw Research
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair